ncRNA name | CARM1 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | Western blot, qRT-PCR, immunofluorescence, immunohistochemistry, siRNA transfection, Hoechst staining |
Expression pattern | associated |
Functional description | Silencing of CARM1 expression by siRNA and pharmacological inhibition of CARM1 activity abolished high-glucose-induced RPE cell apoptosis. |
PubMed ID | 25072916 |
Year | 2014 |
Title | High-glucose-induced CARM1 expression regulates apoptosis of human retinal pigment epithelial cells via histone 3 arginine 17 dimethylation: role in diabetic retinopathy. |
Drug-related ncRNA | NO |
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